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Table 7 The odds table of the simulation model.

From: A hidden two-locus disease association pattern in genome-wide association studies

Model

BB

Bb

bb

Model

BB

Bb

bb

AA

α

αθ 21

αθ 21 θ 22

AA

α

αθ b

Aa

αθ 11

αθ 11 θ 21

αθ 11 θ 21 θ 22

Aa

αθ a

αθ a θ b

aa

αθ 11 θ 12

αθ 11 θ 12 θ 21

αθ 11 θ 12 θ 21 θ 22

aa

  1. The parameters α, θ11, θ12, θ21, and θ22 control the prevalence p(D) (Equation(18)) and the heritability h2 (Equation(19)). For simplicity, let θ11 = θ12 = θ a , θ21 = θ22 = θ b