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Table 2 The mean MCC and BDT raw scores and Z-scores obtained by FunFOLD are compared with those obtained by each CASP8 function prediction group - as in Table 1 except for CASP8 targets containing only metal ligand s.

From: FunFOLD: an improved automated method for the prediction of ligand binding residues using 3D models of proteins

Group ID N Mean score for group Mean score for FunFOLD Increase in mean score Mean Z-score for group Mean Z-score for FunFOLD P-value
(raw score)
P-value
(Z-score)
1 - p-value
(raw score)
1 - p-value
(Z-score)
   MCC BDT MCC BDT MCC BDT MCC BDT MCC BDT MCC BDT MCC BDT MCC BDT MCC BDT
FN407 14 0.764 0.981 0.799 0.710 0.035 0.029 1.064 1.099 1.197 1.218 0.541 0.447 0.541 0.553 0.459 0.553 0.459 0.447
FN202 14 0.654 0.582 0.798 0.761 0.145 0.233 0.869 0.803 1.185 1.349 0.025 0.009 0.047 0.035 0.975 0.991 0.953 0.965
FN034 13 0.620 0.460 0.862 0.819 0.241 0.359 0.641 0.430 1.330 1.522 0.007 0.002 0.005 0.002 0.993 0.998 0.995 0.998
FN417 15 0.143 0.283 0.744 0.710 0.331 0.427 0.183 -0.050 1.070 1.218 0.002 0.001 0.004 0.001 0.998 0.999 0.996 0.999
FN450 15 0.302 0.198 0.744 0.710 0.441 0.512 0.070 -0.077 1.070 1.218 0.000 0.000 0.028 0.032 1.000 1.000 0.972 0.968
FN325 14 0.367 0.318 0.798 0.761 0.432 0.443 0.055 0.052 1.185 1.349 0.002 0.002 0.005 0.005 0.998 0.998 0.995 0.995
FN057 13 0.201 0.189 0.783 0.742 0.582 0.553 -0.470 -0.446 1.165 1.324 0.000 0.000 0.000 0.000 1.000 1.000 1.000 1.000
FN163 12 0.178 0.169 0.685 0.647 0.507 0.478 -0.485 -0.444 0.976 1.110 0.000 0.001 0.000 0.001 1.000 0.999 1.000 0.999
FN483 12 0.066 0.071 0.699 0.656 0.633 0.585 -0.546 -0.552 1.023 1.116 0.001 0.001 0.008 0.002 0.999 0.999 0.992 0.998
FN108 13 0.119 0.092 0.783 0.761 0.664 0.669 -0.566 -0.594 1.172 1.349 0.000 0.000 0.001 0.001 1.000 1.000 0.999 0.999
FN242 15 0.138 0.157 0.744 0.710 0.609 0.554 -0.583 -0.437 1.070 1.218 0.000 0.000 0.000 0.000 1.000 1.000 1.000 1.000
FN105 15 0.004 0.030 0.744 0.710 0.739 0.680 -0.929 -0.818 1.070 1.218 0.000 0.000 0.000 0.000 1.000 1.000 1.000 1.000
FN086 13 -0.017 0.025 0.805 0.760 0.822 0.735 -1.092 -0.884 1.228 1.394 0.000 0.000 0.000 0.000 1.000 1.000 1.000 1.000