Figure 5From: CASCADE_SCAN: mining signal transduction network from high-throughput data based on steepest descent methodOsmolyte synthesis pathway. (A) The osmolyte synthesis pathway obtained from the KEGG database. The darker nodes indicate nodes in the KEGG osmolyte synthesis pathway but not detected by CASCADE_SCAN. (B) The CASCADE_SCAN output for the osmolyte synthesis pathway (83% recall and 67% precision). The darker nodes indicate nodes detected by CASCADE_SCAN but not in the KEGG osmolyte synthesis pathway. (PPI score threshold: 0.800, credible PPI score threshold: 0.980, DFS path length: 5, network size threshold: 30, seed proteins: MSN2, PBS2 and SLN1).Back to article page