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Table 5 The identified genes by AIC or BIC in their 5 common detected pathways

From: Pathway-based analysis using reduced gene subsets in genome-wide association studies

Pathway

Set size

Subset size

Identified genes

Cytokine Network

17

5/1

IL13, IL4, IL9, IL5, IL2

Jak-STAT signaling pathway

126

25/5

IL13, IL23R, IFNE1, STAT2, IL12B, IL4, IL9, IL29, IL5, IL6, IL5RA, IL2, PIK3R5, PIK3R2, EP300, PIK3CG, CSF2RB, TSLP, CNTFR, IFNA21, OSMR, IFNGR1, PIAS4, PIK3CB, SOCS4

Dendritic cells in regulating TH1 and TH2 Development

19

4/1

IL13, IL4, IL5, ANPEP

Cytokine-cytokine receptor interaction

208

49/6

IL13, IL23A, IL23R, IL1R2, IL12B, IFNE1, IL4, IFNA21, PF4V1, IL9, IL29, INHBA, IL5, FAS, OSMR, CCL22, FLT3, TNFRSF21, CSF1, CXCL11, CNTFR, IL1B, IL18RAP, TGFB2, CCL23, IL8RB, IL5RA, IL6, IL11RA, IL2, TNFRSF19, EGF, CCL3, IFNAR2, CCR6, CSF1R, TNFRSF8, PDGFRA, CSF2RB, TNFSF8, CCL1, TSLP, TNFRSF1A, KDR, IL17RB, IFNGR1, TNFRSF11B, IL22RA2, PDGFRB

Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility

21

3/1

RAD50, BRCA2, RAD9A

  1. Column "subset size" (# by AIC/# by BIC) presents the subset sizes selected by AIC and BIC, respectively. Column "selected genes" presents the identified genes by AIC and BIC, where genes with underline denote the ones selected by both AIC and BIC, and genes with no underline denote the ones selected only by AIC.