Geometric Accuracy vs. Modularity of Predicted Complexes. Plot of geometric accuracy against global modularity across a range of parameters for five algorithms: MINE (red), MCODE (black), NEMO (blue), CFinder (green), MCL (yellow), and SPICi (purple). See text for details on different algorithms. A) S. cerevisiae FYI network, evaluated using MIPS complexes. B). C. elegans interactome network from WI8, evaluated using GO Cellular Component annotations with 3-100 gene members.