Skip to main content

Table 1 Comparing the error detection performance of HMM-FRAME, Genewise, and FragGeneScan

From: HMM-FRAME: accurate protein domain classification for metagenomic sequences containing frameshift errors

 

HMM-FRAME:

G20

HMM-FRAME:

self-trained

GeneWise

FragGeneScan

seq-sen

95.25%

90.6%

53.8%

83.04%

base-sen

85.08%

82.4%

 

53.39%

seq-FP

0.154%

0

0.001%

0.7%

base-FP

2.1%

0.003%

 

59.57%

  1. Sensitivity and FP rate of each program when detecting annotated insertion and deletion errors in nifH genes. seq-sen: sequence-level sensitivity. base-sen: base-level sensitivity. seq-FP: sequence-level FP rate. base-FP: base-level FP rate. The score cutoff of Genewise is set to zero to maximize the sensitivity. As Genewise has low sequence-level sensitivity, we did not evaluate its performance at the base-level.