|
(a)
| | |
|---|
| |
Cases
|
Controls
|
|
Subjects with at least One Affected Gene in Z
|
ΣI(x
i
(Z))
|
ΣI(y
i
(Z))
|
|
Subjects without any Affected Genes in Z
|
m
1
- ΣI(x
i
(Z))
|
m
0
- ΣI(y
i
(Z))
|
|
All Subjects
|
m
1
|
m
0
|
|
(b)
| | |
| |
Cases
|
Controls
|
|
Affected Genes in Z
|
Σx
i
(Z)
|
Σy
i
(Z)
|
|
Affected Genes outside Z
|
n
1
- Σx
i
(Z)
|
n
0
- Σy
i
(Z)
|
|
All Affected Genes
|
n
1
|
n
0
|
- (a) This table summarizes the cross-tabulation between the disease status (cases vs. controls) and the location of each gene affected by CNVs (inside vs. outside a scanning window Z) in terms of subject number. x
i
(Z) and y
i
(Z) denote to the number of genes in a window Z that were affected by CNVs of the i th case and control, respectively. m
1
and m
0
denote the total number of subjects with genes affected by CNVs in cases and controls, respectively. "Affected genes" mean genes affected by CNVs in a sample. I(a) is an indicator variable taking the value 1 if a > 0 and 0 otherwise.
- (b) This table summarizes the cross-tabulation between disease status (cases vs. controls) and the location of each gene affected by CNVs (inside vs. outside a scanning window Z) in terms of a gene count. x
i
(Z) and y
i
(Z) denote the number of genes in a window Z that were affected by CNVs of the i th case and control, respectively. n
1
and n
0
denote the total number of genes affected by CNVs in cases and controls, respectively. "Affected genes" mean genes affected by CNVs.
