Skip to main content

Table 4 Expected Number of Genes Affected by Deletions in the Most Likely Gene Cluster per Case and Control Compared with Each Observation

From: A scan statistic to extract causal gene clusters from case-control genome-wide rare CNV data

(1) Cluster size = 776      
  Observations    CRR   
   1.0 2.0 3.0 4.0 5.0
Case 0.054 0.078 0.144 0.203 0.203 0.254
Control 0.011 0.078 0.077 0.076 0.076 0.076
(2) Cluster size = 500      
  Observations    CRR   
   1.0 2.0 3.0 4.0 5.0
Case 0.054 0.050 0.095 0.137 0.174 0.209
Control 0.011 0.050 0.050 0.049 0.049 0.048
(3) Cluster size = 300      
  Observations    CRR   
   1.0 2.0 3.0 4.0 5.0
Case 0.054 0.030 0.058 0.085 0.110 0.134
Control 0.011 0.030 0.030 0.029 0.029 0.029
(4) Cluster size = 200      
  Observations    CRR   
   1.0 2.0 3.0 4.0 5.0
Case 0.054 0.020 0.039 0.058 0.076 0.093
Control 0.011 0.020 0.020 0.020 0.019 0.019
(5) Cluster size = 100      
  Observations    CRR   
   1.0 2.0 3.0 4.0 5.0
Case 0.054 0.010 0.020 0.029 0.039 0.048
Control 0.011 0.010 0.010 0.010 0.010 0.010
  1. This table compares the expected number of genes affected by CNVs in the most likely gene cluster per case and control with each observation. The expected numbers were calculated from the disease model for CRR = 1.0, 2.0, 3.0, 4.0, or 5.0 and cluster size = 100, 200, 300, 500, or 776 (776 = size of the most likely cluster).