BMC Bioinformatics

Table 4 Expected Number of Genes Affected by Deletions in the Most Likely Gene Cluster per Case and Control Compared with Each Observation

From: A scan statistic to extract causal gene clusters from case-control genome-wide rare CNV data

(1) Cluster size = 776
	Observations			CRR
		1.0	2.0	3.0	4.0	5.0
Case	0.054	0.078	0.144	0.203	0.203	0.254
Control	0.011	0.078	0.077	0.076	0.076	0.076
(2) Cluster size = 500
	Observations			CRR
		1.0	2.0	3.0	4.0	5.0
Case	0.054	0.050	0.095	0.137	0.174	0.209
Control	0.011	0.050	0.050	0.049	0.049	0.048
(3) Cluster size = 300
	Observations			CRR
		1.0	2.0	3.0	4.0	5.0
Case	0.054	0.030	0.058	0.085	0.110	0.134
Control	0.011	0.030	0.030	0.029	0.029	0.029
(4) Cluster size = 200
	Observations			CRR
		1.0	2.0	3.0	4.0	5.0
Case	0.054	0.020	0.039	0.058	0.076	0.093
Control	0.011	0.020	0.020	0.020	0.019	0.019
(5) Cluster size = 100
	Observations			CRR
		1.0	2.0	3.0	4.0	5.0
Case	0.054	0.010	0.020	0.029	0.039	0.048
Control	0.011	0.010	0.010	0.010	0.010	0.010

This table compares the expected number of genes affected by CNVs in the most likely gene cluster per case and control with each observation. The expected numbers were calculated from the disease model for CRR = 1.0, 2.0, 3.0, 4.0, or 5.0 and cluster size = 100, 200, 300, 500, or 776 (776 = size of the most likely cluster).

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