Figure 5From: A Beta-mixture model for dimensionality reduction, sample classification and analysisGraphical view of the model. The first probe of a probe pair belonging to class (a1, a2) reaches the states L, M and H with probabilities , and , respectively, and each state emits a methylation value from a corresponding beta-distribution (denoted in the figure by ). Sample index i is suppressed for clarity. Then, transition to the state of the second probe happens according to the transition probabilities and similarly to the first probe, a methylation value is emitted from a beta-distribution.Back to article page