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Table 6 Top ranking co-occurring domains in high confidence binding sites from yeast.

From: Binding Site Prediction for Protein-Protein Interactions and Novel Motif Discovery using Re-occurring Polypeptide Sequences

Domain Name A

Domain Name B

DOMINE

Src homology-3 domain

Src homology-3 domain

Known

Src homology-3 domain

Uncharacterised conserved protein UCP037464, actin patch protein 1

Novel

Src homology-3 domain

Adenylate cyclase-associated CAP, N-terminal

Known

Src homology-3 domain

EF-Hand 1, calcium-binding site

Novel

Src homology-3 domain

Protein of unknown function DUF3210

Known

Src homology-3 domain

BTB/POZ fold

Novel

Src homology-3 domain

Septin

Known

Src homology-3 domain

C2 calcium/lipid-binding domain, CaLB

Novel

Src homology-3 domain

Serine/threonine-protein kinase-like domain

Known

Homeobox

Transcription factor, MADS-box

Known

  1. Binding sites included in this analysis had DM ≤ 0.20. Among interacting domain pairs in all sites, 10 out of 15 (66.7%) pairs are reported in the DOMINE database
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BMC Bioinformatics

ISSN: 1471-2105

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