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Table 2 Excerpt of sample StralSV output "profile" file for positions 229-269 from poliovirus RdRp analysis

From: StralSV: assessment of sequence variability within similar 3D structures and application to polio RNA-dependent RNA polymerase

#

AA

ord

Rname

rnk

s/+

d/+

2nd/+

3rd/+

+/n

+

nv

variety

LSV_P:

L

229

229

2

14.7

72

14.7

7

35.9

143

6

GLIAHF

LSV_P:

F

230

230

1

81.9

81.9

5.2

3.2

38.9

155

7

FMYVLXI

LSV_P:

A

231

231

2

19.1

73.9

19.1

3.2

39.4

157

5

SAYDC

LSV_P:

F

232

232

3

13.2

54.5

19.1

13.2

64.6

257

8

YTFVALDI

LSV_P:

D

233

233

1

100

100

0

0

68.3

272

1

D

LSV_P:

Y

234

234

2

21.7

55.1

21.7

17.8

69.3

276

5

TYVIL

LSV_P:

T

235

235

3

9.1

52.2

33

9.1

69.3

276

6

RSTKAE

LSV_P:

G

236

236

4

8.3

50.4

17.4

8.3

69.3

276

9

CDAGNRKQX

LSV_P:

Y

237

237

4

10.1

55.1

15.9

13.4

69.3

276

7

FHWYCAG

LSV_P:

D

238

238

1

97.1

97.1

1.4

1.4

69.3

276

3

DYE

LSV_P:

A

239

239

3

14.9

59.8

20.3

14.9

69.3

276

4

STAG

LSV_P:

S

240

240

3

13.7

59

16.2

13.7

68.1

271

6

TFSNQR

LSV_P:

L

241

241

4

7.4

55.7

16.2

8.1

68.1

271

8

VWILQHMC

LSV_P:

S

242

242

3

8.8

60.4

16.1

8.8

68.6

273

8

TPSQCHKN

LSV_P:

P

243

243

3

13.4

51.3

15.9

13.4

69.6

277

7

EGPRSQW

LSV_P:

A

244

244

3

12.6

42.2

16.3

12.6

67.8

270

12

NWASRDPIVKCQ

LSV_P:

W

245

245

3

10.9

55.5

17.5

10.9

68.8

274

7

DLWVAFH

LSV_P:

F

246

246

4

10.7

49.8

19.2

11.4

70.6

281

8

IRLFMVCT

LSV_P:

E

247

247

5

6.4

51.6

15.7

7.8

70.6

281

10

RDKAEQNSVH

LSV_P:

A

248

248

3

15.7

48

21

15.7

70.6

281

9

VLATIGCNH

LSV_P:

L

249

249

3

10.7

51.6

25.6

10.7

70.6

281

6

EILAMS

LSV_P:

K

250

250

3

7.5

54.1

10.9

7.5

66.8

266

10

ECKLGIMFQA

LSV_P:

M

251

251

2

13

60.3

13

9.2

60.1

239

8

SMDEAKXY

LSV_P:

V

252

252

2

12.1

75.3

12.1

4

56

223

7

IVGAEYL

LSV_P:

L

253

253

2

23.3

62.8

23.3

6.3

56

223

5

YLMIQ

LSV_P:

E

254

254

2

10.7

65.1

10.7

7.4

54

215

10

QEDVLKATYH

LSV_P:

K

255

255

2

16.3

63.4

16.3

5.9

50.8

202

10

CKANYTRIDE

LSV_P:

I

256

256

4

9.9

60.3

12.1

11.3

35.4

141

7

CLFIYGR

LSV_P:

G

257

257

2

39.2

45.1

39.2

13.7

12.8

51

4

SGYD

LSV_P:

F

258

258

1

85.7

85.7

14.3

0

5.3

21

2

FY

LSV_P:

G

259

259

1

100

100

0

0

3.5

14

1

G

LSV_P:

D

260

260

1

77.8

77.8

11.1

11.1

4.5

18

3

DAN

LSV_P:

R

261

261

1

77.8

77.8

11.1

11.1

4.5

18

3

RMG

LSV_P:

V

262

262

1

56.1

56.1

15.9

8.5

20.6

82

8

VQSPKTIR

LSV_P:

D

263

263

2

14

32

14

13

25.1

100

10

KDVQWNTCAS

LSV_P:

Y

264

264

2

16.2

41.9

16.2

12.4

26.4

105

8

LYVITAFH

LSV_P:

I

265

265

1

32.7

32.7

28.3

11.5

28.4

113

7

IFALQTP

LSV_P:

D

266

266

2

23

44.2

23

8.8

28.4

113

9

EDIKNVASQ

LSV_P:

Y

267

267

2

15.3

37.8

15.3

14.4

27.9

111

9

TYDNRHLAS

LSV_P:

L

268

268

1

57.3

57.3

28.2

4.5

27.6

110

8

LSMHVIYX

LSV_P:

N

269

269

4

12.6

36.9

14.6

12.6

25.9

103

9

LCVNMTISQ

  1. #: file name; AA: query amino acid; ord: sequence position number; Rname: PDB residue name; rnk: rank (position of the query amino acid in the "variety" list); s/+: percent of all residues corresponding to query; d/+: percent of dominant residue; 2nd/+: percent of second most dominant residue; 3rd/+: percent of third most dominant residue; +/n: percent of total templates selected in given experiment contributing to data at a given position; +: total number of templates contributing to data at a given position; nv: total number of amino acid variants; variety: list of variants in order of frequency.