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Table 4 Effect of window_size on sequence variability in SCOP-categorized structure fragments at position N297.

From: StralSV: assessment of sequence variability within similar 3D structures and application to polio RNA-dependent RNA polymerase

Position: 297, Window: 80, Categories: 33, PDB templates: 399, SCOP_IDs: 320

Templates

all PDB templates

e.8 templates

RNA-dependent RNA polymerase

dsRNA phage RNA-dependent RNA polymerase

DNA polymerase I

Reverse transcriptase

Templates not e.8

ScopID

 

e.8

e.8.1.4

e.8.1.6

e.8.1.1

e.8.1.2

 

max LGA

 

100.0

100.0

76.9

57.0

59.2

76.8

ave LGA

 

75.4

85.2

75.1

57.0

56.4

57.8

ave ID

 

27.3

37.3

13.4

3.7

18.6

6.2

matches

 

51

61

40

31

39

35

AA

572

160

85

32

2

41

160

A

1

1

  

1

  

C

8

     

3

D

1

      

E

3

     

1

F

67

42

  

1

41 1

5

G

44

32

 

32 2

   

H

14

5

5 3

   

8

I

19

     

9

K

2

     

2

L

11

     

5

M

2

     

2

N

224

80

80 4

    

P

       

Q

15

     

14

R

82

     

49

S

       

T

15

     

4

V

54

     

50

W

       

Y

10

     

8

X

       
  1. 1F297 (N = 41): reverse transcriptase of HIV
  2. 2G297 (N = 32): dsRNA phage RNA-dependent RNA polymerase of phi6
  3. 3H297 (N = 5): RdRp of lambda 3
  4. 4N297 (N = 80): RdRp proteins from HCV (21), FM (8), lambda3 (5), polio (6), BVDV (3), Norwalk virus (3), rhinovirus (3), rabbit hemorrhagic fever virus (2), IBDV (1)