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Table 2 Comparison of estimators from the simulations.

From: Proportion statistics to detect differentially expressed genes: a comparison with log-ratio statistics

 

Good

Acceptable

Unacceptable

Exponential

 

, EBA

Poisson

, EBA

, edgeR, DESeq

Binomial

, EBA

edgeR

DESeq

Normal

, EBA

 

  1. Four estimators (, and ) and three methods (EBA, edgeR, and DESeq) were used under four distributional assumptions (Exponential, Poisson, Binomial, and Normal). The performance rating (Good, Acceptable, Unacceptable) was judged on the basis of Type I error and power. See Table 1 for an example of the estimators and why the ratings were judged as shown. Additional data for judging the ratings is given in Additional file 1.