Gebiss graphical user interface. The standard ImageJ interface (a) is used to open an input stack before Gebiss is launched. The major modules of Gebiss divide the interface into tabs. The "Slice-based GT Specification" tab (b) is devoted to 2D ground truth creation, where each ROI of an object can be specified by a different threshold. 3D ground truth creation is possible using the "Object-based GT Specification" tab (c), which is coupled with a 3D visualisation window (inset). The numerical performance evaluation is implemented into the "Benchmark" tab (d), that prompts a MS and a GT labelled stack as an input (inset), and returns various performance measures in a tabular format.