Table 1 General comparison of different approaches to flux coupling analysis
From: FFCA: a feasibility-based method for flux coupling analysis of metabolic networks
Method name | Preprocessing | Type of linear program and solution | Further distinguishing of partial and full coupling required? | Postprocessing for reversible reactions? |
|---|---|---|---|---|
MMB-FCA | computing MMBs + reaction classification | n/a | No | No |
EFP-FCA | splitting reversible reactions | MILP, optimal | Yes | Yes |
FCF | splitting reversible reactions | LP, optimal | No | Yes |
W-FCF | n/a | LP, optimal | No | No |
WR-FCF/WRP-FCF | reaction classification | LP, optimal | No | No |
FFCA | reaction classification | LP, feasible | Yes | No |