HomPPI: a class of sequence homology based protein-protein interface prediction methods

BMC Bioinformatics

Table 4 The Proportion of Interface Residues in Datasets used in this Study.

Dataset	Number of Interface Residues^a	Total Number of Residues^b	% Interface Residues
Nr6505	145,498	1,377,630	10.6%
Benchmark180	6,401	43,013	14.9%
Trans135	6,460	55,217	11.7%
Oblig94	10,273	55,400	18.5%
Disordered S1 ^c	585	1,171	50.0%
Disordered S2 ^c	1,797	11,400	15.8%

^a When a chain interacts with more than one other chain, the interfaces are counted separately. For example, for protein complex 2phe C:AB, the interface of C with A and the interface of C with B are regarded as two disordered interfaces.
^b Residues that missing from PDB structures are not counted.
^c For disordered interface datasets S1 and S2, only disordered interfaces are counted.

ISSN: 1471-2105