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Table 4 Number of hits selected in McMaster Test assay for the μ- 2.29SD threshold (i.e., threshold used by the McMaster competition organizers to select the 96 original average hits) after the application of the B-score correction, depending on the α parameter

From: Systematic error detection in experimental high-throughput screening

α

Original hits

Obtained hits

Preserved hits

Added hits

Removed hits

0.01

96

357

79

278

17

0.05

96

419

79

340

17

0.1

96

411

79

332

17

0.2

96

417

76

341

20

  1. The t-test was carried out to detect systematic error.