From: Semantic inference using chemogenomics data for drug discovery
RDF Statements | Explanation |
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wo:ctdcid9681 rdf:type wo:ChemicalCompound. wo:querycmpd wo:isSimilarTo wo:ctdcid9681; wo:hasSimilarity "1.000". wo:ctdcid9681 wo:hasName "Methysergide". wo:HTR1B rdf:type wo:Gene; wo:isrelatedTo wo:cid9681; wo:isInferredFrom "pubmedid8743744". wo:Autistic_Disorder rdf:type wo:Disease; wo:isAssociatedWith wo:HTR1B; wo:isInferredFrom "pubmedid19038234". | A Methysergide-Autistic Disorder relationship is inferred via rule 2 (gene HTR1B). The similar compound (cid = 9681) is Methysergide itself with similarity = 1, it co-occurs with gene HTR1B in a same paper (pubmed id = 8743744), and HTR1B and Autistic_Disorder are co-occurring in another same paper (pubmed id = 19038234). Then we use rule 2 to establish such relations; |
wo:ctdcid11865408 rdf:type wo:ChemicalCompound. wo:querycmpd wo:isSimilarTo wo:ctdcid11865408; wo:hasSimilarity "0.774". wo:ctdcid11865408 wo:hasName "Metergoline". wo:HTR1B rdf:type wo:Gene; wo:isrelatedTo wo:cid11865408; wo:isInferredFrom "pubmedid1330643". wo:Autistic_Disorder rdf:type wo:Disease; wo:isAssociatedWith wo:HTR1B; wo:isInferredFrom "pubmedid19038234". | A Methysergide-Autistic Disorder relationship is also inferred via rule 2 (again via HTR1B). Although this is the same relationship, a different evidence path considered (we will do path ranking on these evidence paths later); |
wo:cid5486180 rdf:type wo:ChemicalCompound. wo:querycmpd wo:isSimilarTo wo:cid5486180; wo:hasSimilarity "0.929". wo:cid5486180 wo:isActiveIn wo:aid410. wo:aid410 rdf:type wo:BioAssay; wo:hasName "p450-cyp1a2". wo:CYP1A2 rdf:type wo:Gene. wo:aid410 wo:hasGene wo:CYP1A2. wo:CYP1A2 wo:isAssociatedWith wo:Lymphoma. wo:Lymphoma rdf:type wo:Disease. | A Methysergide-Lymphoma relationship is inferred by rule1 (via CYP1A2). |