Skip to main content

Table 1 Mutation contexts

From: New words in human mutagenesis

Mutation type Subcontext Context Minimal contrast Mutation bias
    (NG) (WG) (NG) (WG)
C > T C C G 5.1 4.7 5.1 4.7
G > A G CG 5.1 4.7 5.1 4.7
T > C T TG AT TG 2.1 2.2 3.5 3.6
T > C AT A AT AG 1.8 1.8 3.3 3.5
A > G CAA CAA T 2.1 2.2 3.5 3.6
A > G TA T CTA T 1.8 1.8 3.3 3.5
A > C A CA A CAA 1.9 1.9 3.4 3.4
T > G TGT TTGT 1.9 1.9 3.5 3.4
  1. This table presents contexts of mutations that have minimal contrast values higher than 1.7 and mutation bias values higher than 3. The mutated nucleotides are in bold and underlined. "NG" stands for "No Genes" (regions that do not belong to any known genes, CpG islands, or 1000 bp flanking regions of known genes) and "WG" stands for "Whole Genome". The subcontext is the one that is used for the minimal contrast calculation and is the same for the no gene and whole genome datasets for all mentioned contexts.