Figure 3
From: DNACLUST: accurate and efficient clustering of phylogenetic marker genes
Distribution of cluster MSAs based on their average pairwise distance. Figures 3a, 3b and 3c show the distribution of sampled cluster multiple sequence alignments based on their average pairwise distance for thresholds 99%, 97% and 95%, respectively. The figures show that DNACLUST cluster MSAs (thick blue line) are tighter (i.e. have smaller average pairwise distance) than UCLUST cluster MSAs (thick red lines). Furthermore computing a "traditional" MSA using ClustalW from the clusters produced by DNACLUST and UCLUST results in an overestimation of the distances between sequences (dashed lines).