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Table 3 List of positively selected genes that intersect DivE's predicted accelerated regions.

From: Detection of lineage-specific evolutionary changes among primate species

Gene symbol

Gene full name

Encode region

Subtree

under

selection

No. of orthologous sequences

P-value

SERPINB7

serpin peptidase inhibitor, clade B (ovalbumin), member 7

ENr122

new world monkeys

13

<.0001

SLC22A4

solute carrier family 22 (organic cation/ergothioneine transporter), member 4

ENm002

orangutan

14

<.0001

UGT1A8

UDP glucuronosyltransferase 1 family, polypeptide A8

ENr131

baboon

7

<.0001

LILRA4

leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4

ENm007

human-orangutan

6

<.0001

APOA4

apolipoprotein A-IV

ENm003

macaque

13

<.0001

HBQ1

hemoglobin, theta 1

ENm008

chimp

14

<.0001

F7

coagulation factor VII (serum prothrombin conversion accelerator)

ENr132

macaque

11

<.0001

C21orf13

(LCA5L)

Leber congenital amaurosis 5-like

ENr133

mouse lemur

13

0.0004

CGN

cingulin

ENr231

dusky titi

13

0.0004

LILRB4

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4

ENm007

vervet-baboon

6

0.0007

AC006985.5

(HEATR7B1)

HEAT repeat containing 7B1

ENr131

prosimians

9

0.0007

ARHGDIG

Rho GDP dissociation inhibitor (GDI) gamma

ENm008

simians

10

0.0017

F8

coagulation factor VIII, procoagulant component

ENm006

owl monkey

10

0.0026

SYT8

synaptotagmin VIII

ENm011

new world monkeys

8

0.0030

C22orf30 (PRR14L)

proline rich 14-like

ENm004

simians

12

0.0039

HBZ

hemoglobin, zeta

ENm008

macaque

4

0.0043

LILRB5

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5

ENm007

macaque

3

0.0068

DEPDC5

DEP domain containing 5

ENm004

human-colobus monkey

12

0.007

RPS9

ribosomal protein S9

ENm007

human-colobus monkey

13

0.0227

DDX43

DEAD (Asp-Glu-Ala-Asp) box polypeptide 43

ENr223

new world monkeys

12

0.0246

  1. Positive selection was determined with the codeml program from the PAML package. The first column gives the ENCODE gene symbol followed in parentheses by the corresponding Genbank gene symbol (if different). The fourth column in the table shows the name of the subtree predicted to be accelerated by DivE. If there are multiple species in the selected tree, the clade is specified by the two species whose most common ancestor form the clade's root, or by the clade's name as specified in Figure 1.