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Figure 4 | BMC Bioinformatics

Figure 4

From: Modeling measurement error in tumor characterization studies

Figure 4

DNA methylation of MLH1 in the Colon-CFR. A) Scatterplot of MLH1 Percent Methylated Reference (PMR) against ALU C(t) value for 198 MSI-H colon cancer samples from Seattle. (a)-(e) Histograms of the PMR values by 5 quintiles of ALU C(t). B) a plot of SD of MLH1 PMR by quintile of ALU C(t) (grey bars) and by sliding windows (black circles). C) Back-to-back histograms of the MLH1 PMR in females and males for 198 MSI-H tumors from the Colon CFR (Seattle site). One sample with a PMR = 302 lies outside the range of the figure. Black dots denote the overall mean (including the sample not displayed.)

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