TY - JOUR AU - Missirian, Victor AU - Comai, Luca AU - Filkov, Vladimir PY - 2011 DA - 2011/07/14 TI - Statistical Mutation Calling from Sequenced Overlapping DNA Pools in TILLING Experiments JO - BMC Bioinformatics SP - 287 VL - 12 IS - 1 AB - TILLING (Targeting induced local lesions IN genomes) is an efficient reverse genetics approach for detecting induced mutations in pools of individuals. Combined with the high-throughput of next-generation sequencing technologies, and the resolving power of overlapping pool design, TILLING provides an efficient and economical platform for functional genomics across thousands of organisms. SN - 1471-2105 UR - https://doi.org/10.1186/1471-2105-12-287 DO - 10.1186/1471-2105-12-287 ID - Missirian2011 ER -