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Table 2 Performance comparison of CAMBa to other methods using default parameters on Rice and Wheat

From: Statistical Mutation Calling from Sequenced Overlapping DNA Pools in TILLING Experiments

 

Rice

Wheat

Method

Pred

Conf

FP

FN

Sens

Spec

Pred

Conf

FP

FN

Sens

Spec

CAMBa

75

10

7

7

90.67

99.96

107

36

8

8

92.52

99.82

Outlier

75

8

20

20

73.33

99.89

107

36

8

8

92.52

99.82

CRISP

0

0

0

75

0.00

100.00

121

32

33

19

82.24

99.28

VarScan

3

0

3

75

0.00

99.98

30

10

3

80

25.23

99.93

ComSeq

9599

10

9531

7

90.67

47.15

154

36

55

8

92.52

98.79

Poisson

6889

8

6834

20

73.33

62.10

218

35

122

11

89.72

97.33

  1. Performance comparison of CAMBa to other methods using default parameters, on the Rice (left) and the Wheat data sets. The column abbreviations are as in Table 1. All methods are evaluated on their ability to predict the carrier of each candidate mutation, except CRISP, which cannot make such predictions.