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Table 2 Performance comparison of CAMBa to other methods using default parameters on Rice and Wheat

From: Statistical Mutation Calling from Sequenced Overlapping DNA Pools in TILLING Experiments

  Rice Wheat
Method Pred Conf FP FN Sens Spec Pred Conf FP FN Sens Spec
CAMBa 75 10 7 7 90.67 99.96 107 36 8 8 92.52 99.82
Outlier 75 8 20 20 73.33 99.89 107 36 8 8 92.52 99.82
CRISP 0 0 0 75 0.00 100.00 121 32 33 19 82.24 99.28
VarScan 3 0 3 75 0.00 99.98 30 10 3 80 25.23 99.93
ComSeq 9599 10 9531 7 90.67 47.15 154 36 55 8 92.52 98.79
Poisson 6889 8 6834 20 73.33 62.10 218 35 122 11 89.72 97.33
  1. Performance comparison of CAMBa to other methods using default parameters, on the Rice (left) and the Wheat data sets. The column abbreviations are as in Table 1. All methods are evaluated on their ability to predict the carrier of each candidate mutation, except CRISP, which cannot make such predictions.