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Table 3 Performance comparison of CAMBa to other methods using default parameters on Wheat with increased variance

From: Statistical Mutation Calling from Sequenced Overlapping DNA Pools in TILLING Experiments

Method Wheat with increased variance
  Pred Conf FP FN Sens Spec
CAMBa 113 28 36 30 71.96 99.21
Outlier 113 20 58 52 51.40 98.73
CRISP 86 25 17 38 64.49 99.63
VarScan       
ComSeq 743 30 661 25 76.64 85.51
Poisson 60 18 11 58 45.79 99.76
  1. Performance comparison of CAMBa to other methods using default parameters, on the Wheat data set after artificially increasing the coverage variance. The column abbreviations are as in Table 1. All methods are evaluated on their ability to predict the carrier of each candidate mutation, except CRISP, which cannot make such predictions. We were unable to report results for VarScan due to technical issues in generating a modified pileup of reads.