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Figure 3 | BMC Bioinformatics

Figure 3

From: Bio::Homology::InterologWalk - A Perl module to build putative protein-protein interaction networks through interolog mapping

Figure 3

Validation Procedure. Schematics showing the rationale for the creation of the known positive sets for validation. (A) Complete PPI datasets for two genomes G i and G j are retrieved. Only PPIs conserved across the two species through orthology are retained. PPI pairs in G i satisfying this property constitute the known positive set . (B) PPI information between the IDs in is assumed unknown. (C) The gene IDs in are the input for Bio::Homology::InterologWalk. (D) The putative PPI set obtained is compared with the experimental interaction known positive set.

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BMC Bioinformatics

ISSN: 1471-2105

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