| | |
Mamanova et al.
|
Marioni et al.
|
Bullard et al.
|
Lee et al
|
Nagalakshmi et al.
|
|---|
|
Dinuc
|
Read type
|
STD-Seq
|
FRT- Seq
|
Marioni kidney
|
Marioni liver
|
MAQC2 brain
|
MAQC2 UHR
|
MAQC3 UHR
|
yeast RH
|
yeast oligodT
|
yeast RH
|
|
AA
|
unique
|
4.5
|
9.3
|
6.1
|
8.4
|
2.1
|
2.2
|
2.7
|
5.2
|
10.8
|
10.3
|
|
AA
|
multi
|
4.5
|
10.3
|
6.7
|
7.9
|
2.5
|
2.6
|
3.0
|
4.0
|
10.1
|
7.9
|
|
AC
|
unique
|
1.5
|
5.2
|
1.4
|
1.4
|
0.9
|
1.0
|
0.8
|
1.4
|
6.4
|
5.4
|
|
AC
|
multi
|
2.1
|
5.8
|
1.3
|
1.3
|
1.0
|
1.0
|
0.9
|
1.3
|
6.0
|
5.2
|
|
AG
|
unique
|
2.5
|
7.1
|
3.0
|
3.2
|
2.2
|
2.2
|
2.2
|
2.3
|
7.8
|
5.9
|
|
AG
|
multi
|
3.3
|
6.6
|
2.8
|
3.0
|
2.1
|
2.2
|
2.1
|
2.0
|
6.9
|
4.8
|
|
AT
|
unique
|
3.4
|
7.2
|
5.7
|
6.8
|
1.9
|
2.0
|
2.4
|
4.7
|
7.4
|
5.7
|
|
AT
|
multi
|
3.9
|
5.4
|
6.0
|
7.0
|
2.3
|
2.4
|
2.7
|
4.3
|
7.8
|
5.0
|
|
CA
|
unique
|
8.9
|
5.4
|
7.7
|
7.0
|
10.7
|
10.6
|
10.5
|
8.7
|
10.6
|
11.1
|
|
CA
|
multi
|
7.3
|
5.2
|
6.2
|
5.6
|
10.0
|
11.0
|
10.9
|
7.8
|
10.9
|
10.2
|
|
CC
|
unique
|
9.6
|
4.0
|
7.8
|
5.8
|
10.8
|
10.2
|
10.4
|
5.6
|
6.0
|
6.3
|
|
CC
|
multi
|
9.0
|
4.2
|
7.2
|
5.4
|
9.6
|
8.8
|
9.4
|
7.3
|
5.5
|
7.7
|
|
CG
|
unique
|
5.5
|
2.3
|
4.4
|
3.4
|
10.0
|
10.1
|
10.4
|
7.2
|
2.0
|
2.9
|
|
CG
|
multi
|
5.8
|
2.9
|
5.2
|
4.6
|
9.9
|
8.7
|
9.1
|
8.6
|
2.2
|
4.3
|
|
CT
|
unique
|
12.2
|
5.8
|
13.3
|
11.6
|
13.1
|
13.0
|
13.3
|
12.2
|
7.9
|
7.4
|
|
CT
|
multi
|
13.0
|
6.0
|
13.0
|
11.2
|
13.4
|
13.5
|
13.7
|
13.1
|
7.8
|
9.1
|
|
GA
|
unique
|
4.0
|
6.7
|
4.9
|
5.3
|
5.2
|
5.4
|
4.5
|
7.0
|
4.9
|
5.4
|
|
GA
|
multi
|
4.5
|
6.1
|
4.7
|
5.2
|
5.3
|
5.8
|
4.7
|
6.2
|
5.0
|
5.3
|
|
GC
|
unique
|
12.5
|
5.7
|
7.7
|
6.9
|
11.7
|
12.0
|
10.0
|
8.6
|
2.2
|
3.0
|
|
GC
|
multi
|
11.2
|
6.2
|
8.1
|
7.6
|
11.1
|
11.6
|
9.8
|
10.3
|
1.8
|
3.2
|
|
GG
|
unique
|
13.0
|
5.0
|
9.2
|
8.8
|
12.0
|
11.9
|
11.8
|
8.7
|
3.8
|
4.2
|
|
GG
|
multi
|
11.7
|
6.0
|
9.8
|
9.6
|
11.7
|
11.4
|
11.1
|
8.6
|
4.1
|
5.2
|
|
GT
|
unique
|
9.8
|
5.7
|
10.1
|
9.5
|
8.4
|
8.6
|
8.4
|
12.3
|
4.2
|
5.2
|
|
GT
|
multi
|
9.2
|
5.0
|
10.4
|
10.0
|
9.2
|
9.1
|
9.1
|
11.8
|
4.6
|
6.9
|
|
TA
|
unique
|
1.6
|
5.2
|
3.7
|
4.4
|
1.1
|
1.1
|
1.3
|
2.2
|
10.8
|
10.8
|
|
TA
|
multi
|
1.7
|
3.8
|
4.3
|
5.0
|
1.4
|
1.1
|
1.4
|
2.1
|
11.2
|
10.3
|
|
TC
|
unique
|
2.1
|
6.8
|
3.0
|
3.2
|
2.1
|
2.2
|
2.3
|
2.9
|
3.9
|
4.8
|
|
TC
|
multi
|
2.8
|
6.0
|
2.7
|
3.0
|
2.1
|
2.2
|
2.3
|
3.0
|
3.8
|
4.2
|
|
TG
|
unique
|
6.1
|
6.9
|
5.6
|
5.6
|
4.7
|
4.9
|
5.4
|
5.1
|
7.9
|
8.4
|
|
TG
|
multi
|
5.7
|
8.2
|
5.5
|
5.6
|
4.8
|
5.3
|
5.8
|
4.7
|
8.7
|
7.8
|
|
TT
|
unique
|
2.7
|
11.4
|
6.3
|
8.4
|
2.5
|
2.5
|
3.6
|
5.9
|
3.5
|
3.3
|
|
TT
|
multi
|
4.1
|
12.1
|
6.2
|
7.9
|
2.9
|
2.9
|
4.0
|
4.8
|
3.4
|
2.7
|
- Percentage was calculated by SAMStat [33]. Uniquely mapped reads and multi-mapped reads were separated in the calculation but showed similar pattern. Bold numbers indicates significantly over-represented dinucleotide with p-values less than or equal to 10-100 from a Binomial test described in [34].
