Test data set for the comparison study. (a) The GRN of m = 100 genes in E. coli is illustrated in the lower right panel as an adjacency matrix. Each entry marks a regulatory link between two associated genes. The upper panel shows the corresponding expression time series (simulated in the noise-free case and normalized to values between 0 (coded in black) and 1 (coded in white)). An example of the time series of the lon gene (gene number 2), including a spline interpolation is shown in the lower left panel. (b) The graphical representation of the network is shown in addition.