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Table 2 A joint feature ranking of the DL compound descriptors.

From: Multi-target QSAR modelling in the analysis and design of HIV-HCV co-inhibitors: an in-silico study

Features Ranking values
# of non-H 0.167148
# of 2-degree cyclic atoms 0.118946
degree of cyclization 0.100268
# of non-H polar bonds 0.056622
# of rotatable bonds 0.049770
# of carbons in cap fragments 0.047428
# of cap fragments 0.043447
# of 3-degree cyclic atoms 0.040664
# of N and O atoms 0.038882
# of H-bond acceptors 0.038103
# of fragments 0.033010
maximum cap fragment size 0.032459
# of 2-degree acyclic atoms 0.027549
# of 3-degree acyclic atoms 0.021673
# of 3-level bonding patterns 0.018798
total SSSR size 0.017162
total number of 3-8 membered rings 0.017162
# of cyclic fragments 0.016538
# of 1-level bonding patterns 0.016382
# of H-bond donors 0.016217
total number of 3 to 8 unsaturated rings 0.016072
# of aromatic systems 0.014930
# of N with # of H > 0 0.012320
# of hydroxyl groups 0.009301
maximum SSSR size 0.008863
# of linkers 0.008807
# of 2-level bonding patterns 0.006729
total number of 3 to 8 saturated rings 0.004750