Skip to main content

Table 5 More # of non-H, # of 2-degree cyclic atoms, degree of cyclization and # of non-H polar bonds could increase the potency of HIV Integrase Inhibitors.

From: Multi-target QSAR modelling in the analysis and design of HIV-HCV co-inhibitors: an in-silico study

Precursor Structure pKi
#11
pIC50: 5.82
+ 0.75%
(× 21.2)
#189
pIC50: 5.53
+ 0.74%
(× 21.2)
#188
pIC50: 4.43
+ 0.73%
(× 21.3)
\