Skip to main content
Figure 5 | BMC Bioinformatics

Figure 5

From: Ranking insertion, deletion and nonsense mutations based on their effect on genetic information

Figure 5

Distribution of mutations on the human tumour repressor TP53 with respect to their respective loss of information scores. The upper panel shows the distribution of D for 95 somatic, 49 cell-line and 15 germline NM in the TP53 tumour suppressor. The lower panel show the distribution of D for 1256 somatic, 127 cell-line and 36 germline FS indels reported for TP53 protein. These mutations are associated with a wide range of cancers.

Back to article page