Figure 5From: Ranking insertion, deletion and nonsense mutations based on their effect on genetic informationDistribution of mutations on the human tumour repressor TP53 with respect to their respective loss of information scores. The upper panel shows the distribution of D for 95 somatic, 49 cell-line and 15 germline NM in the TP53 tumour suppressor. The lower panel show the distribution of D for 1256 somatic, 127 cell-line and 36 germline FS indels reported for TP53 protein. These mutations are associated with a wide range of cancers.Back to article page