Figure 6

Comparison of the average stationary behavior of the CPME model that incorporates deterministic reaction dynamics with the steady state of the structured continuum model. [I _ex ] = 24 μM for all simulations and all other parameters as in Table 3. Panel (a): Predictions from the cell population model agree with those from the structured continuum model when the average values for A/V and [O] _T are used. For the solid S-shaped curve, the average values for A/V and [O] _T were taken from the population simulations. For the dashed curve, the average values were estimated using Eqs. 8 and 9. Panel (b): a representative bimodal NDF and the corresponding averages and standard deviation.