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Table 1 Functional assignment of tissue specific over- and underexpression spots using the GO-terms biological process/molecular function (see also Figure 3d and 3e).

From: Expression cartography of human tissues using self organizing maps

Spota

Over-/underexpressed in tissuea

Biological process/Molecular function (overrepresented genes set)b

A

Nervous system samples (45-67), pituatary gland(5)

Nervous system development

Synaptic transmission

Transmission of nerve impuls

B

Muscle related: small intestine (12), tongue (24), heart atrium&ventricle (29, 30), muscle (31, 32)

Structural constituent of muscle

System process

Striated muscle contraction

C1

Liver (10), kidney cortex&medulla (8,9)

Substrate specific transporter activity

Carboxylic acid metabolic process

Organic acid metabolic process

C2

Pancreas (6)

Carboxypeptidase activity

Carboxylesterase activity

Digestion

D

Adipose tissue (1-3), epithelium tissue (18-26), ovary (27)

Tissue development

Organ development

Ectoderm development

E

Male reproduction: testis (28)

Sexual reproduction

Reproduction

Gamete generation

F

Immune system samples (34-44)

Immune system process

Immune response

Defense response

G

Pituatary gland(5)

Hormone activity

DNA fragmentation during apoptosis

Apoptotic nuclear changes

H

Bone marrow (40), thymus (43)

Cell cycle process

Mitotic cell cycle

Cell cycle phase

a

Immune system (34-44)

Regulation of axonogenesis

Regulation of structural morphogenesis

Regulation of neurogenesis

b

Various samples without clear assignment, e.g., sexual reproduction and muscle

Microtubule binding

Protein maturation

Tubulin binding

c

Epithelium and muscle tissues

RNA metabolic process

Biopolymer metabolic process

RNA processing

  1. a Spots are assigned in Figure 3d and 3e. Over- and underexpression spots are labeled using upper and lower case letters, respectively.
  2. b Top-three overrepresented gene sets