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Figure 1 | BMC Bioinformatics

Figure 1

From: Visualizing Meta-Features in Proteomic Maps

Figure 1

Network and pathway maps of a 2DGE-MS experiment. (A) In the network map of Scenario 1, large spheres indicate proteins that belong to a specific network, whereas their color (red/green/blue) indicates proteins' up/down/no regulation. (B) A 2D gel image annotated with the accession numbers of selected identified proteins. Such images, very often found in proteomics publications, are difficult for the user to explore and need effort to indicate the interesting proteins/spots. The maps presented in Scenario 1 use the detected spots of this 2D gel. (C) The result of a right click action on a specific sphere is a pop-up menu that contains user-selected information. In this case, the menu shows the Object ID, Accession Number, Protein Name, Protein Type and Biological Process of a protein. (D) The user can select any one of the available features to appear in the pop up menus of the spheres. (E) In the pathway map of Scenario 1, large spheres indicate proteins that belong to a specific pathway, whereas their color (red/green/blue) indicates their protein type (also shown in the color bar). The result of a click action on a specific sphere is highlighted corresponding table row, which contains all the features of the clicked sphere/protein.

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