Rigorous assessment and integration of the sequence and structure based features to predict hot spots

BMC Bioinformatics

Table 6 Comparison of different methods for hot spots prediction on independent test set

Method	P	R	F1
Robetta	0.66	0.49	0.56
FOLDEF	0.50	0.44	0.47
Cho's method	0.53	0.62	0.57
Sequence-based SVM	0.69	0.68	0.68
Structure-based SVM	0.62	0.70	0.66
All features SVM	0.65	0.63	0.64

ISSN: 1471-2105