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Table 3 DCGs with existing evidence of T2D-relevance.

From: Link-based quantitative methods to identify differentially coexpressed genes and gene Pairs

gene DCP.dC Expression fold change Reported Relevance
Rapgef4 1.29 0.81 T2D-related
Nr5a1 1.28 0.56 T2D-related
Cd28 1.21 1.21 KEGG rno04940
Ucp2 1.18 1.31 T2D-related
Pparg 1.17 1.05 T2D-related; T2D-associated
RT1-Bb 1.16 0.74 KEGGrno04940
Cox6a2 1.15 0.57 KEGG rno00190
Bdnf 1.13 2.13 T2D-related
Gad1 1.12 0.23 KEGG rno04940
Prkaa1 1.12 1.03 KEGG rno04910
Prkab1 1.11 0.52 KEGG rno04910; T2D-related
RT1-Da 1.09 1.99 KEGG rno04940
Nos3 1.09 0.76 T2D-related
Cox6c1 1.09 0.62 KEGG rno00190
Inpp5d 1.08 2.36 KEGG rno04910; T2D-related
Arnt 1.07 0.71 T2D-related
Sstr5 1.06 1.77 T2D-related
Lipe 1.06 2.04 KEGG rno04910; T2D-related
Cacna1a 1.06 0.55 KEGG rno04930
RT1-Ba 1.05 1.71 KEGG rno04940
Tnfrsf1a 1.05 1.07 T2D-related
Il6 1.05 1.77 T2D-related
Gip 1.05 0.63 T2D-related
Cacna1c 1.05 0.74 KEGG rno04930
Mapk10 1.03 0.79 KEGG rno04930; KEGG rno04910; T2D-related
Nras 1.02 0.71 KEGG rno04910
Serpine1 1.02 2.07 T2D-related
Kcnj5 1.01 0.74 T2D-related
Hla-dma 1.01 2.84 KEGG rno04940
  1. Included genes appeared in at least one of the following sources: KEGG T2D-related pathways (Rno04930: type II diabetes mellitus; rno04940: type I diabetes mellitus; rno04910: insulin signaling pathway; rno00190: oxidative phosphorylation); a self-compiled set of 425 T2D-related genes in rat; a list of 52 T2D-associated genes. The lists of "T2D-related" genes and "T2D-associated" genes are provided in "Additional File 6: 52 T2D-associated genes & 425 rat T2D-related genes".