NoD: a Nucleolar localization sequence detector for eukaryotic and viral proteins

Scott, Michelle S; Troshin, Peter V; Barton, Geoffrey J

doi:10.1186/1471-2105-12-317

BMC Bioinformatics

Table 2 Detail of NoD predictions on the multi-organism testing dataset assembled

From: NoD: a Nucleolar localization sequence detector for eukaryotic and viral proteins

Organism	Protein Accession	Name	Experimentally determined NoLS position	NoD prediction	Ref^a
Homo sapiens	NP_001012333	Midkine	129-143	120-143	[19]
Homo sapiens	NP_055701	NSA2	10-41	no NoLS	[20]
Homo sapiens	NP_055701	NSA2	131-154	133-155	[20]
Homo sapiens	NP_872604	RASSF5	51-100	78-98	[21]
Homo sapiens	NP_037541	follistatin	93-116 ^b	98-121	[22]
Homo sapiens	CAA41051	histone H2B	28-35	15-42	[23]
Mus musculus	NP_001012495	Cxcl12	98-118	92-119	[24]
Mus musculus	NP_081208	NoBP	220-262	230-255 and 276-306	[25]
Mus musculus	NP_082355	aminopeptidase O	688-725	682-712	[26]
Dictyostelium discoideum	XP_002649205	eIF6	31-64	27-49	[27]
Dictyostelium discoideum	XP_002649205	eIF6	246-252	295-320	[27]
Aplysia kurodai	B0FRH7	ApLLP	1-19	1-21	[28]
Aplysia kurodai	B0FRH7	ApLLP	90-120	96-120	[28]
Trypanosome brucei	CAD21884	ESAG8	48-79	no NoLS	[14]
Trypanosome cruzi	XP_817097	Met-III	1-19	No NoLS	[29]
Trypanosome cruzi	XP_817097	Met-III	146-191	No NoLS	[29]
Solanum lycopersicum	Q944N1	LHP1	141-171	141-165 and 276-296	[30]
Arabidopsis thaliana	NP_001078269	HMGB1	1-47	22-60	[31]
Bovine herpesvirus 1	CAA90914	BICP27	86-97	75-108	[32]
Human Adenovirus C	YP_001551773	E4orf4	66-75	61-82	[33]
SARS	P59633	Non-structural protein 3b	134-154	No NoLS	[34]
HTLV-1	BAH85789	Tof	71-98	No NoLS	[35]
Human herpes simplex	P08353	Gamma-1 34.5 protein	1-16	1-22	[36]
Human adenovirus 2	P68950	protein VII	93-112	90-117	[15]
African Swine Fever Virus	AAA87288	I14L	1-14	1-26	[37]
PRRSV (porcine)	AAD00244	N protein	41-48	1-21 and 32-59	[38]
Tomato Leaf Curl Java Virus	BAD90868	Capsid protein	1-30	no NoLS	[39]
Potato leafroll virus	P11624	Capsid protein	17-31	10-64	[40]
Marek's disease virus type 1	AAS01627	MEQ protein	62-78	22-47 and 52-81	[41]
Avian Infectious Bronchitis Virus	CAC39307	N protein	71-78	347-377	[42]
Betanodavirus GGNNV	NP_689432	Protein alpha	23-31	10-40	[43]

^a Ref: Reference reporting the experimental NoLS identification
^b In [22], the NoLS for follistatin is reported at positions 64-87. These correspond to the positions in the protein once the signal peptide has been removed.

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ISSN: 1471-2105

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