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Table 3 Accuracy of NoD predictions in all organisms investigated

From: NoD: a Nucleolar localization sequence detector for eukaryotic and viral proteins

  distinct protein count NoLS count TPa count FPb count Sensitivity PPVc Specificityd
A. Eukaryotes
Mammals e 8 9 8 1 0.89 0.89 0.88
   H. sapiens 5 6 5 0 0.83 1.0 1.0
   M. musculus 3 3 3 1 1.0 0.75 0.67
Amoeba e 1 2 1 1 0.5 0.5 0.0
Dictyostelium discoideum 1 2 1 1 0.5 0.5 0.0
Molluscs e 1 2 2 0 1.0 1.0 1.0
   A. kurodai 1 2 2 0 1.0 1.0 1.0
Trypanosomes e 2 3 0 0 0 N/A 1.0
   T. brucei 1 1 0 0 0 N/A 1.0
   T. cruzi 1 2 0 0 0 N/A 1.0
Plants e 2 2 2 1 1.0 0.67 0.5
   S. lycopersicum 1 1 1 1 1.0 0.50 0.0
   A. thaliana 1 1 1 0 1.0 1.0 1.0
B. Viruses
   Mammalian host 8 8 6 1 0.75 0.86 0.88
   Plant host 2 2 1 0 0.5 1.0 1.0
   Avian host 2 2 1 2 0.5 0.33 0.0
   Fish host 1 1 1 0 1.0 1.0 1.0
  1. a TP: true positive
  2. b FP: false positive
  3. c PPV: positive predictive value
  4. d The specificity was calculated as the number of proteins considered for which no FP was identified divided by the number of proteins considered (this defines all non NoLS regions as negatives).
  5. e For each of the count columns, the top row of each of the subsections in the Eukaryotes section represents the sum of the rows below it belonging to this subsection.