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Figure 4 | BMC Bioinformatics

Figure 4

From: RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

Figure 4

The directed graphical model used by RSEM. The model consists of N sets of random variables, one per sequenced RNA-Seq fragment. For fragment n, its parent transcript, length, start position, and orientation are represented by the latent variables G n , F n , S n and O n respectively. For PE data, the observed variables (shaded circles), are the read lengths ( and ), quality scores ( and ), and sequences ( and ). For SE data, , , and are unobserved. The primary parameters of the model are given by the vector θ, which represents the prior probabilities of a fragment being derived from each transcript.

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