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Table 1 A survey of the distribution of the co-occurrence derived results

From: Development of a classification scheme for disease-related enzyme information

Enzyme class
(EC) name
EC Diseases found with enzyme relation EC numbers found with disease relation Distinct combination of EC number and disease (a) Distinct combination of EC number, disease and reference Overall EC numbers in BRENDA (b) Representation Quotient a/b
Oxidoreductases 1 2,646 429 23,214 159,215 1,393 0.76
Transferases 2 2,862 506 23,939 283,794 1,369 0.78
Hydrolases 3 3,439 737 55,036 406,831 1,523 1.64
Lyases 4 1,721 169 6,053 31,487 494 0.56
Isomerases 5 1,350 64 3,531 22,230 186 0.86
Ligases 6 712 74 1,578 7,340 161 0.45
  1-6 4,061 1,979 112,805 910,897 5,126  
  1. a/b: The quotient of the combination of EC number and disease (a) and the overall EC numbers in BRENDA (b).