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Table 7 The DrugBank entries for drug targets in comparison with the entries of DRENDA

From: Development of a classification scheme for disease-related enzyme information

DRENDA confidence level EC numbers in DRENDA DRENDA/DrugBank agreement EC number, disease and PubMed reference combination DRENDA/DrugBank agreement DRENDA/DrugBank agreement with consideration of diseases
1 1,622 863 (53.2%) 422,601 307,477 (72.8%) 18,834 (4.5%)
2 1,516 831 (54.8%) 345,421 251,460 (72.8%) 17,018 (4.9%)
3 1,227 710 (57.9%) 182,532 137,701 (75.4%) 12,466 (6.8%)
4 1,183 694 (58.7%) 158,143 120,760 (76.4%) 11,448 (7.2%)
  1. The entries of DRENDA which have are assigned to the category therapeutic application put in relation to DrugBank entries. The amount of EC numbers and combinations of EC number, disease and PubMed reference are listed together with the quantity of coinciding DrugBank entries for drug target enzymes with and without consideration of matching disease.