Figure 3

The ABP nodes extracted from the reconstructed flavonoid subnetwork of Arabidopsis. Figure 3 is a detailed part of the self-contained subnetwork showing the subset of nodes or metabolites in the 24 EMs that constitute the ABP. The compound groups that are not directly related to anthocyanins, are shown as greyed-out side branches from the ABP. Highlighted is an example of one anthocyanin EM leading to the formation of cyanidin 3-O-sophoroside. The names of compounds and reactions are as assigned in the AraCyc database [63]. Enzymes: CHS: Chalcone Synthase; CHI: Chalcone isomerase; F3H: Flavanone 3-hydroxylase; F3'H: Flavanone 3'-hydroxylase; DFR: Dihydroflavonol reductase; ANS: Anthocyanidin synthase; LDOX: Leucoanthocyanidin dioxygenase; FLS: Flavonol synthase; UDPG: UDP-glycosyltransferase; 3-UGT: Anthocyanidin 3-O-glucosyltransferase; 5-GT: Anthocyanin 5-O-glucosyltransferase (Hexosyltransferase); Ss5MaT1: Anthocyanin 5-O-glucoside 6-O-malonyltransferase (Acyltransferase); 2.4.1.- Hexosyltransferases; 2.3.1.- Acyltransferases: Transferring groups other than aminoacyl groups. (Pg) indicates enzymes corresponding to reactions related to pelargonidin-type compounds; (Cy) indicates enzymes corresponding to reactions related to cyanidin-type compounds.