An integrative approach to ortholog prediction for disease-focused and other functional studies

BMC Bioinformatics

Table 1 The number of Drosophila-human ortholog pairs predicted using individual published ortholog tools or the integrative tool DIOPT

	*D.mel-H.sap* relationships	Unique relationships*	*D.mel* genes covered	*H.sap* genes covered
Compara	16880	3994	8416	9826
Homologene	5423	82	5015	4762
Inparanoid	10204	695	5855	7441
IsoBase	9051	1639	8065	7251
OMA	5673	296	4499	5222
orthoMCL	12853	2352	6435	7890
Phylome	8690	1496	4560	6251
RoundUp	7480	398	5383	6706
TreeFam	12894	1347	7156	9106
DIOPT	28605	NA	9724	12971

D.mel, Drosophila melanogaster; H.sap. Homo sapiens
* Unique Relationships, relationships not predicted by any of the other eight tools.

ISSN: 1471-2105