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Table 1 The number of Drosophila-human ortholog pairs predicted using individual published ortholog tools or the integrative tool DIOPT

From: An integrative approach to ortholog prediction for disease-focused and other functional studies

  D.mel-H.sap
relationships
Unique
relationships*
D.mel genes
covered
H.sap genes
covered
Compara 16880 3994 8416 9826
Homologene 5423 82 5015 4762
Inparanoid 10204 695 5855 7441
IsoBase 9051 1639 8065 7251
OMA 5673 296 4499 5222
orthoMCL 12853 2352 6435 7890
Phylome 8690 1496 4560 6251
RoundUp 7480 398 5383 6706
TreeFam 12894 1347 7156 9106
DIOPT 28605 NA 9724 12971
  1. D.mel, Drosophila melanogaster; H.sap. Homo sapiens
  2. * Unique Relationships, relationships not predicted by any of the other eight tools.