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Table 2 Disease genes from OMIM and GWAS (sorted by # of human genes)

From: An integrative approach to ortholog prediction for disease-focused and other functional studies

Disease category # of disease terms # of human genes # of Drosophila genes # of Drosophila genes filter1 # of Drosophila genes filter2
Congenital, Hereditary, and Neonatal Diseases and Abnormalities 3518 2803 2614 2076 1890
Nervous System Diseases 1921 1816 1901 1437 1339
Disease risk factor, diagnosis or treatment 273 1459 1768 1398 1292
Musculoskeletal Diseases 1523 1332 1433 1110 1035
Eye Diseases 1410 1214 1356 1038 953
Skin and Connective Tissue Diseases 1100 1117 1349 1039 949
Digestive System Diseases 901 1063 1397 1058 935
Otorhinolaryngologic Diseases 933 879 996 750 704
Male Urogenital Diseases 782 863 1069 838 765
Cardiovascular Diseases 843 856 1140 869 756
Female Urogenital Diseases and Pregnancy Complications 771 830 1041 819 741
Nutritional and Metabolic Diseases 490 701 896 698 608
Stomatognathic Diseases 686 637 761 559 528
Mental Disorders 344 626 906 610 543
Neoplasms 500 616 673 493 463
Pathological Conditions, Signs and Symptoms 539 608 489 337 319
Hemic and Lymphatic Diseases 628 584 775 614 545
Endocrine System Diseases 442 511 627 451 427
Immune System Diseases 323 480 523 371 337
Respiratory Tract Diseases 447 479 639 493 445
Trait 208 434 536 374 336
Virus Diseases 23 65 48 41 39
Bacterial Infections and Mycoses 19 32 36 24 24
Parasitic Diseases 7 16 28 19 18
Substance-Related Disorders 7 14 17 13 13