Table 2 Disease genes from OMIM and GWAS (sorted by # of human genes)
From: An integrative approach to ortholog prediction for disease-focused and other functional studies
Disease category | # of disease terms | # of human genes | # of Drosophila genes | # of Drosophila genes filter1 | # of Drosophila genes filter2 |
|---|---|---|---|---|---|
Congenital, Hereditary, and Neonatal Diseases and Abnormalities | 3518 | 2803 | 2614 | 2076 | 1890 |
Nervous System Diseases | 1921 | 1816 | 1901 | 1437 | 1339 |
Disease risk factor, diagnosis or treatment | 273 | 1459 | 1768 | 1398 | 1292 |
Musculoskeletal Diseases | 1523 | 1332 | 1433 | 1110 | 1035 |
Eye Diseases | 1410 | 1214 | 1356 | 1038 | 953 |
Skin and Connective Tissue Diseases | 1100 | 1117 | 1349 | 1039 | 949 |
Digestive System Diseases | 901 | 1063 | 1397 | 1058 | 935 |
Otorhinolaryngologic Diseases | 933 | 879 | 996 | 750 | 704 |
Male Urogenital Diseases | 782 | 863 | 1069 | 838 | 765 |
Cardiovascular Diseases | 843 | 856 | 1140 | 869 | 756 |
Female Urogenital Diseases and Pregnancy Complications | 771 | 830 | 1041 | 819 | 741 |
Nutritional and Metabolic Diseases | 490 | 701 | 896 | 698 | 608 |
Stomatognathic Diseases | 686 | 637 | 761 | 559 | 528 |
Mental Disorders | 344 | 626 | 906 | 610 | 543 |
Neoplasms | 500 | 616 | 673 | 493 | 463 |
Pathological Conditions, Signs and Symptoms | 539 | 608 | 489 | 337 | 319 |
Hemic and Lymphatic Diseases | 628 | 584 | 775 | 614 | 545 |
Endocrine System Diseases | 442 | 511 | 627 | 451 | 427 |
Immune System Diseases | 323 | 480 | 523 | 371 | 337 |
Respiratory Tract Diseases | 447 | 479 | 639 | 493 | 445 |
Trait | 208 | 434 | 536 | 374 | 336 |
Virus Diseases | 23 | 65 | 48 | 41 | 39 |
Bacterial Infections and Mycoses | 19 | 32 | 36 | 24 | 24 |
Parasitic Diseases | 7 | 16 | 28 | 19 | 18 |
Substance-Related Disorders | 7 | 14 | 17 | 13 | 13 |