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Table 3 Disease phenotypes associated with Drosophila genes in the literature

From: An integrative approach to ortholog prediction for disease-focused and other functional studies

Mesh # of fly genes # of fly genes with human ortholog(s) # of fly genes shared disease categories with their human ortholog % fly genes with human ortholog(s) % fly genes shared disease categories with their human ortholog
Neoplasms 681 636 592 93% 93%
Pathological Conditions, Signs and Symptoms 2105 1713 1566 81% 91%
Nervous System Diseases 1179 1004 878 85% 87%
Digestive System Diseases 105 94 81 90% 86%
Otorhinolaryngologic Diseases 18 14 12 78% 86%
Mental Disorders 470 448 378 95% 84%
Congenital, Hereditary, and Neonatal Diseases and Abnormalities 1234 1100 900 89% 82%
Cardiovascular Diseases 139 126 103 91% 82%
Stomatognathic Diseases 20 20 16 100% 80%
Skin and Connective Tissue Diseases 148 123 98 83% 80%
Immune System Diseases 112 84 64 75% 76%
Respiratory Tract Diseases 8 8 6 100% 75%
Disorders of Environmental Origin 760 642 466 84% 73%
Hemic and Lymphatic Diseases 100 96 69 96% 72%
Endocrine System Diseases 163 144 103 88% 72%
Nutritional and Metabolic Diseases 577 452 310 78% 69%
Female Urogenital Diseases and Pregnancy Complications 558 413 276 74% 67%
Virus Diseases 38 32 21 84% 66%
Musculoskeletal Diseases 211 165 106 78% 64%
Male Urogenital Diseases 468 355 221 76% 62%
Bacterial Infections and Mycoses 325 233 99 72% 42%
Eye Diseases 699 590 221 84% 37%
Parasitic Diseases 229 187 21 82% 11%
All Categories 3557 2739 2283 77% 83%