Quantitative utilization of prior biological knowledge in the Bayesian network modeling of gene expression data

BMC Bioinformatics

Table 2 GO and PubMed citation contain information of functional linkage

interval	GO similarity LLS, yeast	LLS, mouse	interval	-log₁₀(p_PubMed)LLS, yeast	LLS, mouse
[1, 1]	1.51	1.62	(4 ∞)	0.25	0.37
[0.2, 1)	-0.71	-0.99	(3 4]	0.13	0.14
[0, 0.2)	-1.61	-2.2	(1 3]	0.07	0.19
			[0 1]	-3.4	-3.6

Log Likelihood Scores of functional linkage in yeast and mouse, for gene pair in different value interval of GO similarity and PubMed co-citation significance. Gene pairs with higher GO similarity or significance of co-citation are more likely to be functionally linked.

ISSN: 1471-2105