Figure 1

Schematic flow-chart of the annotation process. On the left, processes coloured red are performed by Utopia Documents, processes in blue by GPCRDB. On the right, is a screenshot of an annotated paper [29] in the Utopia Documents PDF reader, in which all annotated concepts have been highlighted by pressing the space-bar (annotations appear as red highlights, both in the body of the text and in the document margins).