Coherence score comparisons with/without obviously related GO domain. For the pathway sets, the coherence scores were compared with and without the BP domain annotations. A, The CAS with all the three domains (the x-axis) while CAS_Coherence(BP-) (y-axis) is the CAS computed without BP terms. B, PAS coherence scores with and without BP terms. For the GOcc sets coherence scores were compared with and without (CC-) the use of CC domain annotations. C, CAS coherence; D, PAS coherence.