Quantification of protein group coherence and pathway assignment using functional association

BMC Bioinformatics

Table 2 Examples of concurrent GO terms based on CAS

GO ID	Description	Domain	Concurrent GO terms	Description	Domain	CAS
GO:0004359	glutaminase activity	MF	GO:0006543	glutamine catabolic process	BP	232.37
			GO:0006541	glutamine metabolic process	BP	32.051
			GO:0042819	vitamin B6 biosynthetic process	BP	19.364
			GO:0009065	glutamine family amino acid catabolic process	BP	15.754
			GO:0042816	vitamin B6 metabolic process	BP	11.618
GO:0004134	4-alpha-glucanotransferase activity	MF	GO:0000025	maltose catabolic process	BP	348.56
			GO:0010297	heteroglycan binding	MF	348.56
			GO:0004135	amylo-alpha-1,6-glucosidase activity	MF	348.56
			GO:0004133	glycogen debranching enzyme activity	MF	199.17
			GO:0000023	maltose metabolic process	BP	116.18
GO:0000719	photoreactive repair	BP	GO:0003904	deoxyribodipyrimidine photo-lyase activity	MF	278.84
			GO:0003913	DNA photolyase activity	MF	119.50
			GO:0006290	pyrimidine dimer repair	BP	73.381
			GO:0009650	UV protection	BP	7.536
			GO:0050660	FAD binding	MF	5.163
GO:0000733	DNA strand renaturation	BP	GO:0000405	bubble DNA binding	MF	139.42
			GO:0045002	double-strand break repair via single-strand annealing	BP	92.949
			GO:0000739	DNA strand annealing activity	MF	41.007
			GO:0043140	ATP-dependent 3'-5' DNA helicase activity	MF	36.690
			GO:0000217	DNA secondary structure binding	MF	20.503
GO:0000108	repairosome	CC	GO:0000111	nucleotide-excision repair factor 2 complex	CC	232.37
			GO:0000113	nucleotide-excision repair factor 4 complex	CC	174.28
			GO:0000715	nucleotide-excision repair, DNA damage recognition	BP	126.74
			GO:0031463	Cul3-RING ubiquitin ligase complex	CC	99.588
			GO:0000109	nucleotide-excision repair complex	CC	32.424

For the five GO terms in the left column, top five GO terms with the largest CAS score are listed.

ISSN: 1471-2105