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Table 1 Validation across microarray platforms of Mulcom, Limma and SAM tests

From: Mulcom: a multiple comparison statistical test for microarray data in Bioconductor

  

Mulcom

Limma

SAM

HGF 1 h

Significant genes in Affy

867

672

723

 

Validated in Illumina

150

0

48

HGF 6 h

Significant genes in Affy

681

518

561

 

Validated in Illumina

317

237

100

HGF 24 h

Significant genes in Affy

4

0

82

 

Validated in Illumina

1

0

1

ITGB4 +/-

Significant genes in Affy

26

6

75

 

Validated in Illumina

1

1

0

Total

Significant genes in Affy

1249

956

1006

 

Validated in Illumina

487

246

151

 

True positive rate

39%

26%

15%

  1. Number of genes identified by Mulcom, Limma and SAM tests in the Affymetrix dataset, and the number of validated genes in the Illumina dataset for all the pair-wise comparisons.